Collagen MD Advance Connective Tissue formula 398g

CONNECTIVE TISSUE MATRIX

Collagen is a major physiological structural protein that represents about one-third of the total protein in the body and up to 80% of the connective tissue matrix. Distributed throughout the body, the collagen triple helix is a versatile constituent of the connective tissue matrix in the skin, bones, muscles, tendons, cartilage, ligaments, hair & nails.

Each day the body goes through a natural cycle of collagen breakdown and regeneration but after the age of approximately twenty-five collagen renewal and cell turnover gradually decline. The decline in collagen synthesis is part of the intrinsic aging process resulting in less lean body mass and/or weight gain, joint pain, fine lines, thinning hair, weak nails and loss of skin suppleness. The metabolic needs of an aging or very active body may benefit from supplementary amino acids to support the maintenance, repair and health of the connective tissue and skin matrix.*

As a constituent of the extracellular matrix and connective tissue when Hyaluronic Acid production declines with age, so too does the body’s capacity to retain moisture, a contributing factor to the appearance of fine lines, wrinkles or joint pain. Hyaluronic acid is a glycosaminoglycan with a high affinity for water that’s an important component of all connective tissue. There is approximately 7-15 grams of hyaluronic acid in the average adult’s body with up to thirty percent turned over every day.* Distributed throughout the body, Hyaluronic Acid keeps collagen and elastin hydrated as a biological tissue lubricant in the extracellular matrix.* Hyaluronic Acid also plays a role in the complex process of tissue repair and wound healing.* In the body, one of Hyaluronic Acid’s primary functions is to bind water to tissues as well as lubricate moveable parts of the body such as joints and eyes.* Healthy levels of hyaluronic acid in the skin matrix contribute to its hydrated and glowing appearance.*

ADVANCED CONNECTIVE TISSUE FORMULA

Advanced Connective Tissue Formula is a professional-strength dietary supplement that provides specialized nutritional support to meet the metabolic needs of the connective tissue and skin matrix.* Micronized hydrolyzed Collagen Type I & III is a 100% natural source of 19 concentrated amino acids (beef). Amino acids are the basic building blocks used by the body to maintain, grow and repair tissue.* Collagen Type I & III is an excellent source lysine, alanine, arginine, glycine, proline and hydroxyproline with glycine concentrations 8 times that of milk and proline more than triple that of beef protein food sources* Advanced Connective Tissue Formula is highly bioavailable and bioactive, neutral in taste and comes in an easy to use powder format.*

Advanced Connective Tissue Formula is a rich source of nature's moisturizer, Hyaluronic Acid. Advanced Connective Tissue Formula is fortified with four water-soluble vitamins that are important to the cycle of collagen production and protein metabolism; vitamin C, vitamin B12, folic acid and biotin.* Vitamin C is a cofactor in the Vitamin C-dependant collagen synthesis process.*

• Vitamin C initiates a cascade of events that’s vital to entangle peptides into fibrils so they can be arranged into collagen fibers*. The tissues of the body store less than a one-month supply of vitamin C therefore a deficiency can impact collagen production.*
• Biotin also called Vitamin H or Coenzyme R is one of the B-vitamin family and plays a role in the metabolism of amino acids, energy metabolism and the production of various enzymes.* Biotin helps strengthen hair and nails.*
• Vitamin B12 is involved in fat and protein metabolism, energy production, nerve function, regulation of red blood cells and DNA synthesis.* Vitamin B-12 plays a role in the synthesis of collagen and inadequate vitamin B levels have been shown to decrease collagen formation and a deficiency may also contribute to decreased bone mineral density.*(1, 2)
• Folic Acid also known as Vitamin B9, folate or folacin works with vitamin B12 in several processes in the body.* Folic acid is important to cellular division and a deficiency is associated with cells that can't divide properly.* Follic Acid contributes to bone health, the production and maintenance of new cells (such as red blood cells), RNA and DNA.*

1. Approximately 10-30% of older people may be unable to absorb naturally occurring B12 from foods, so consuming B12-fortified foods or B12 supplements may be required to meet the recommended intake for those over 50 years old.*
2. (2 )Low Plasma Vitamin B12 Is Associated With Lower BMD: The Framingham Osteoporosis Study JOURNAL OF BONE AND MINERAL RESEARCH Volume 20, Number 1, 2005 Published online on October 25, 2004; doi: 10.1359/JBMR.041018